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What are the differences between the currently open call ‘Strategic actions supporting large scale trials’, and the already closed call?

Question details: 
What are the differences between the currently open call ‘Strategic actions supporting large scale trials’, and the already closed call ‘Diagnostic tools for poverty-related diseases’, also a RIA action with two stages?
Answer: 

The ‘Strategic actions’ call supports clinical research activities which are part of a large-scale clinical trial that has the potential to achieve rapid advances in the clinical development of new or improved medical interventions against poverty-related and neglected infectious diseases. In short, the ‘Strategic actions’ call focuses on large-scale clinical trials. The ‘Diagnostics’ call is intended to fund projects that aim to validate the clinical performance and/or implementation of new or improved diagnostic tools and technologies for the detection of any of the PRDs (including as co-infections).